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DelveInsight’s Severe Asthma – Market Insights, Epidemiology, and Market Forecast–2032 report deliver an in-depth understanding of the Severe Asthma, historical and forecasted epidemiology as well as the Severe Asthma market trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.
The Severe Asthma market report provides current treatment practices, emerging drugs, market share of individual therapies, and current and forecasted 7MM Severe Asthma market size from 2019 to 2032. The Report also covers current Severe Asthma treatment practice, market drivers, market barriers, SWOT analysis, reimbursement, market access, and unmet medical needs to curate the best of the opportunities and assesses the underlying potential of the market.
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Asthma is the most common chronic respiratory disease all over the globe. It affects the airways in the lungs, which become inflamed and narrowed due to various triggers, making it harder for air to flow out. It is a complex activity between airway inflammation and airway remodeling that results in airway hyper-responsiveness (AHR), which further leads to variable and excessive airway contraction. The characteristic symptoms of asthma include wheezing, shortness of breath, cough, a sensation of tightness in the chest, straining of neck and chest muscles, rapid breathing, and changes in heart rate.
Based upon response to treatment, severe asthma is further classified into type-2 inflammation and non-type-2 inflammation. Type-2 inflammation includes allergic asthma and eosinophilic asthma (or e-asthma) while non-type-2 inflammation includes non-eosinophilic asthma.
Diagnosis of severe asthma is difficult as careful physiologic characterization of the patient is lacking. In most cases, diagnosis depends on the symptoms and the response to treatment already being administered. Peripheral airway resistance (Rp) measurements, computed tomography, noninvasive magnetic resonance, PET scans, sputum induction, and bronchoscopy help diagnose asthma and related airway inflammation. Various biomarker tests are recommended to determine the asthma phenotype.
Severe Asthma Epidemiological Segmentation
The treatment aims to reduce the symptom burden (i.e., good symptom control while maintaining normal activity levels) and minimize the risk of adverse events such as exacerbations, fixed airflow limitation, and treatment side effects. Guideline-based management of asthma focuses on disease severity and choosing the appropriate medical therapy to control symptoms and reduce the risk of exacerbations. Severe asthmatics require higher doses of inhalers and often require medications (anticholinergics) that relax the muscles around the airways, making it easier to breathe. Long-term usage of combination inhaled controller medications may not be sufficient for treating severe asthmatics, and long-term use of oral steroids carries the risk of increased side effects.
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